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Clinical trials for Aseptic Necrosis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    12 result(s) found for: Aseptic Necrosis. Displaying page 1 of 1.
    EudraCT Number: 2015-000618-23 Sponsor Protocol Number: ORN-01 Start Date*: 2015-05-05
    Sponsor Name:Västra Götalandsregionen/NÄL
    Full Title: Treatment of osteoradionecrosis (ORN) with pentoxifylline and α-tocopherol (PENTO)
    Medical condition: Osteoradionecrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031264 Osteonecrosis PT
    18.0 10022117 - Injury, poisoning and procedural complications 10067352 Osteoradionecrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000887-32 Sponsor Protocol Number: ORN-02 Start Date*: 2015-07-20
    Sponsor Name:Västra Götalandsregionen/NÄL
    Full Title: Prophylactic treatment of osteoradionecrosis (ORN) with pentoxifylline and α-tocopherol (PENTO)
    Medical condition: Osteoradionecrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031264 Osteonecrosis PT
    18.0 10022117 - Injury, poisoning and procedural complications 10067352 Osteoradionecrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022318-22 Sponsor Protocol Number: tutkijalähtöinen tutkimus, Start Date*: 2010-10-20
    Sponsor Name:Maarit Valkealahti / University hospital of Oulu
    Full Title: Tsoledronaatti hoito paikallista kiihtynyttä luunvaihdunta- oireyhtymää sairastavilla potilailla
    Medical condition: Tässä tutkimuksessa esitetään bisfosfonaatti –lääkkeen käyttöä uusissa indikaatioissa. Haemme tällä tutkimussuunnitelmalla lupaa kliiniseen tutkimukseen, jossa selvitetään, mikä on lääkkeen teho h...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10031264 Osteonecrosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019060-37 Sponsor Protocol Number: CH.MAX-FACC.02/2009 Start Date*: 2010-07-09
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Clinical prospective study to evaluate the efficacy of hygienical therapy and metronidazole in addition to antibiotic therapy in patients affected by bisphosponate-associated osteonecrosis of the jaws
    Medical condition: patients affected by bisphosponate-associated osteonecrosis of the jaws and infection.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031264 LLT
    9.1 10021864 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012929-11 Sponsor Protocol Number: PREOB-ON3 Start Date*: 2011-10-17
    Sponsor Name:Bone Therapeutics S.A.
    Full Title: Phase III, pivotal, multicentre, randomised, double-blind controlled Study to evaluate the Efficacy and Safety of Autologous Osteoblastic Cells (PREOB®) Implantation in Early Stage Non Traumatic Os...
    Medical condition: Osteonecrosis of the Femoral Head
    Disease: Version SOC Term Classification Code Term Level
    18.1 10028395 - Musculoskeletal and connective tissue disorders 10031264 Osteonecrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) DE (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000886-35 Sponsor Protocol Number: AloFem Start Date*: 2018-06-27
    Sponsor Name:Enrique Gomez-Barrena
    Full Title: Evaluation of safety, feasibility and preliminary efficacy of MSCs from third party donors in the treatment of patients with osteonecrosis of the femoral head after allogeneic Stem Cell Transplanta...
    Medical condition: Osteonecrosis of the Femoral Head
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031264 Osteonecrosis PT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10003860 Avascular necrosis femoral head LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019415-38 Sponsor Protocol Number: CZOL446HDE38T Start Date*: 2011-03-23
    Sponsor Name:Universitätsklinikum Würzburg
    Full Title: A prospective, bicentric, randomised, primarily double blind, placebo-controlled study to evaluate the efficacy of zoledronic acid for the treatment of bone marrow syndrome
    Medical condition: Determination of efficacy of Zoledronic Acid on the treatment of bone marrow edema syndrome.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10064277 Bone marrow edema syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004817-16 Sponsor Protocol Number: MACI00206 Start Date*: 2008-01-23
    Sponsor Name:Genzyme Europe B.V.
    Full Title: A Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study to Demonstrate the Superiority of Matrix-induced Autologous Chondrocyte Implantation (MACI® implant) versus Arthroscopic Mi...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    13.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) SE (Completed) NL (Completed) PL (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016751-22 Sponsor Protocol Number: ABR30311 Start Date*: 2010-04-01
    Sponsor Name:AMC, divisie Psychiatrie
    Full Title: A double blind, placebo controlled study of memantine in patients with obsessive-compulsive disorder.
    Medical condition: Obsessive-compulsive disorder (OCD)
    Disease: Version SOC Term Classification Code Term Level
    12.0 10030029 OCD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016970-33 Sponsor Protocol Number: MACI00809 Start Date*: 2011-03-17
    Sponsor Name:Genzyme Europe BV
    Full Title: An Extension Protocol for Participants of Genzyme-Sponsored Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study of Matrix-Induced Autologous Chondrocyte Implantation (MACI® impl...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. Osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) CZ (Completed) GB (Completed) SE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2021-000938-34 Sponsor Protocol Number: MYTHS Start Date*: 2021-07-01
    Sponsor Name:AZIENDA OSPEDALIERA AO OSPEDALE NIGUARDA CA' GRANDA
    Full Title: Single blind randomized controlled trial to assess the safety and efficacy of high dose pulse intravenous corticosteroid therapy to treat patients with complicated/fulminant acute myocarditis
    Medical condition: Complicated/fulminant acute myocarditis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10000932 Acute myocarditis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing) BE (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003556-20 Sponsor Protocol Number: RH4131-03 Start Date*: 2014-02-19
    Sponsor Name:Dept. of Intensive Care 4131, Copenhagen University Hospital, Rigshospitalet
    Full Title: Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
    Medical condition: Necrotizing Soft Tissue Infections
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021881 - Infections and infestations 10055648 Necrotizing fasciitis fungal LLT
    16.1 10021881 - Infections and infestations 10052892 Necrotising fasciitis fungal PT
    16.1 10021881 - Infections and infestations 10055647 Necrotizing fasciitis LLT
    16.1 10021881 - Infections and infestations 10055649 Necrotizing fasciitis staphylococcal LLT
    16.1 10021881 - Infections and infestations 10017068 Fournier's gangrene LLT
    16.1 10021881 - Infections and infestations 10028885 Necrotising fasciitis PT
    16.1 10021881 - Infections and infestations 10016229 Fasciitis necrotising LLT
    16.1 10021881 - Infections and infestations 10028886 Necrotising fasciitis NOS LLT
    16.1 10021881 - Infections and infestations 10028888 Necrotising fasciitis streptococcal PT
    16.1 10021881 - Infections and infestations 10028887 Necrotising fasciitis staphylococcal PT
    16.1 10021881 - Infections and infestations 10055650 Necrotizing fasciitis streptococcal LLT
    16.1 10021881 - Infections and infestations 10055643 Fasciitis necrotizing LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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